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What is Gall bladder?
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The gallbladder is a pear-shaped organ that lies beneath the liver in the right-upper
abdomen. The gallbladder is connected to the liver (which produces the bile) by
the hepatic duct. Its function is to store bile. When food containing fat reaches
the small intestine, a hormone called cholecystokinin is produced by cells in the
intestinal wall and is carried to the gall bladder via the bloodstream. The hormone
causes the gall bladder to contract, forcing bile into the common bile duct. A valve,
which opens only when food is present in the intestine, allows bile to flow from
the common bile duct into the duodenum (upper intestine) where it functions in the
process of fat digestion.
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What is cholecystitis?
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Cholecystitis
is an inflammation of the gallbladder wall and nearby abdominal lining. Cholecystitis
can occur suddenly or gradually over many years. Acute cholecystitis is the sudden
onset of inflammation of the gallbladder, resulting in severe, steady upper abdominal
pain (biliary colic), which may occur repeatedly. Chronic cholecystitis is long-standing
inflammation of the gallbladder characterized by repeated attacks of pain (gallbladder
attacks) over a prolonged period.
At least 95% of people with acute cholecystitis have gallstones. Gallstones are
stones which are formed in the gallbladder. The Gall Bladder stores and concentrates
bile. Sometimes the substances contained in bile crystallize in the gall bladder,
forming stones. These small, hard concretions are more common in persons over 40,
especially in women and the obese. Rarely, acute cholecystitis occurs in a person
without gallstones (acalculous cholecystitis). In these cases the cause can be any
major injury, operation or burn, bacterial infection in the bile duct system, tumor
of the pancreas or liver.
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What are the symptoms of cholecystitis?
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A gallbladder attack,
whether in acute or chronic cholecystitis, begins as severe, steady abdominal pain
(biliary colic). The person typically feels a sharp pain when a doctor presses on
the upper right part of the abdomen. The pain may worsen when the person breathes
deeply and often extends to the lower part of the right shoulder blade. The pain
may become excruciating; and may be accompanied by nausea and vomiting. The pain
usually lasts more than 12 hours. Within a few hours, the abdominal muscles on the
right side become rigid. Fever occurs in about one third of people but is less likely
in older people. The fever tends to be mild at first, and then rises gradually to
above 100° F (38° C). Typically, an attack of cholecystitis subsides in
2 to 3 days and completely disappears in a week. If the attack persists, it may
signal a serious complication. This disorder initially produces symptoms similar
to those of indigestion, especially after a fatty meal is consumed. This may be
accompanied by nausea and vomiting. But when a stone becomes lodged in the bile
duct, it produces severe pain. Many people also remain asymptomatic. The symptoms
of cholecystitis may resemble gastric pain but one must always consult their physician
for a proper diagnosis.
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How is it diagnosed?
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Doctors diagnose cholecystitis, both acute and chronic, based on the person's symptoms
and the results of tests that suggest gallbladder inflammation. The physician will
perform a careful abdominal examination to confirm the diagnosis. The enlarged,
tender gallbladder may be felt by the physician through the abdominal wall. Pressure
in the upper right corner of the abdomen may cause the patient to stop breathing
in, due to an increase in pain. This is called Murphy's sign. Besides this, few
diagnostic procedures may be advised. They include :
- Blood tests: Increased levels of white blood cells suggest inflammation or infection
or both. There may also be increase in bilirubin levels.
- Ultrasound (Also called sonography.) - A diagnostic imaging technique which uses
high-frequency sound waves to create an image of the internal organs. Ultrasounds
are used to view internal organs of the abdomen such as the liver spleen, and kidneys
and to assess blood flow through various vessels. Ultrasound scans can also show
thickening of the gallbladder wall, which is typical of chronic cholecystitis.
- Hepatobiliary scintigraphy - Cholescintigraphy is an imaging technique that is useful
when acute cholecystitis is difficult to diagnose. In this test, a radioactive tracer
is injected intravenously and its movement from the liver through the biliary tract
is followed. Images are taken of the liver, bile ducts, gallbladder, and upper part
of the small intestine. If the tracer does not fill the gallbladder, it is presumed
that the cystic duct is obstructed by a gallstone.
- Cholangiography - x-ray examination of the bile ducts using an intravenous (IV)
dye (contrast).
- Endoscopic retrograde cholangiopancreatography (ERCP) - a procedure that allows
the physician to diagnose and treat problems in the liver, gallbladder, bile ducts,
and pancreas. The procedure combines x-ray and the use of an endoscope - a long,
flexible, lighted tube. The scope is guided through the patient's mouth and throat,
then through the oesophagus, stomach, and duodenum. The physician can examine the
inside of these organs and detect any abnormalities. A tube is then passed through
the scope, and a dye is injected which will allow the internal organs to appear
on an x-ray.
- Computed tomography scan (CT or CAT scan) - a diagnostic imaging procedure using
a combination of x-rays and computer technology to produce cross-sectional images
(often called slices), both horizontally and vertically, of the body. A CT scan
shows detailed images of any part of the body, including the bones, muscles, fat,
and organs. CT scans are more detailed than general x-rays.
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How is cholecystitis treated?
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The approach taken to treat cholecystitis depends upon:
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- Extent of the disease
- Age, overall health, and medical history of the patient
- Tolerance of specific medicines, procedures, or therapies
- Expectations for the course of the disease
- Patient's opinion or preference
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For acute cholecystitis, initial treatment includes bowel rest, intravenous hydration,
intravenous antibiotics and pain management. Whether it is acute or chronic cholecystitis,
the physician then takes a step to identify the cause. If the cause is gallstones,
then he may suggest the conventional solution in which the gall bladder itself is
removed. And if the physician feels that it is best to remove the gall bladder,
he may advice the patient to undergo Cholecystectomy after the acute phase subsides.
Cholecystectomy merely means removal of the gallbladder. In acalculous cholecystitis,
immediate surgery is necessary to remove the diseased gallbladder. Cholecystectomy
again can be done by conventional method (also called open method) or by the laparoscopic
method. We wish to provide our patients with complete information about the available
treatments. So we are discussing (below) both the conventional and new methods.
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The conventional method
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The conventional method, also called open method was initially the only standard
treatment. This was the common treatment offered both for gallstone removal or gallbladder
removal. This procedure required a 3 to 7 day stay in the hospital and a 3 to 7
inch incision and scar on the abdomen. The surgeon makes an abdominal incision under
the right side of the rib cage, which cuts through the skin and muscle. The gallbladder
is then located and removed.
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Latest Methods
Laparoscopic Cholecystectomy is now the gold standard treatment and is the commonest
operation performed laparoscopically worldwide. Gynaecologists have long used this
technique to tie the Fallopian tubes and to inspect the female reproductive organs.
Now the use of laparoscopy has been expanded to include removing a diseased gallbladder.
The first documented laparoscopic Cholecystectomy was performed by Erich Mühe
in Germany in 1985. Currently, over 90% of cholecystectomies are performed laparoscopically;
making it the most common procedure performed in general surgery practice.
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It is a minimally invasive approach that involves specialized video equipment and
instruments that allow a surgeon to remove the gallbladder through four tiny incisions,
most of which are less than a half-centimetre in size.
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Before the procedure
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After deciding upon the line of treatment of the case, the physician will explain
the procedure to the patient. He will also give an opportunity to the patient and
his relatives to ask any queries or doubts. In addition to a complete medical history,
the physician may perform a physical examination to ensure that the patient is in
good health. In an otherwise healthy person, little is required to prepare for surgery.
Depending on the age, gender, and health problems, some routine blood tests, an
EKG and a chest x-ray may be needed. In fit patients, the only investigations needed
are ultrasound examination, hemoglobin estimation, and liver function tests. Blood
is also collected for group determination and keeping a couple of bottles on the
standby. Endoscopic retrograde cholangiopancreatography (ERCP) is performed when
ductal stones are suspected on the basis of clinical, biochemical and ultra-sound
criteria. The surgeon will also make note if there is any history of allergy to
any medication or anesthetic agents. One should be very open with their surgeon
and must let him know about all medications he is taking. In general, all blood
thinners need to be stopped 3-5 days before surgery.
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The physician fixes up the surgery date and the patient is given an outline of the
schedule. The patient will be instructed to refrain from eating 8 hours before surgery.
On the day of the surgery, the patient is required to sign a consent form. The patient
is again thoroughly examined by the physician. Based upon the patient's medical
condition, the physician may request the specific preparation. Gallbladder operations
are performed under general anesthesia. An IV line will be placed in the arm for
fluids and then the patient is brought into the operation room.
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During the procedure
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The anesthesiologist and nurses keep using monitors
to check the heart rate and breathing rate during the procedure. These may include
EKG leads, a blood pressure cuff and an oxygen mask. The patient is operated in
the supine position with a steep head-up tilt. A nasogastric tube is inserted and
the stomach aspirated. The tube is kept in the stomach during the operation but
removed at the end of the procedure.
Laparoscopic cholecystectomy requires several small incisions in the abdomen to
allow the insertion of surgical instruments and a small video camera. So, the surgeon
makes a small incision at the navel o insert a thin tube carrying the video camera.
The camera sends a magnified image from inside the body to a video monitor, giving
the surgeon a close-up view of the organs and tissues. The surgeon then inflates
the abdomen with carbon dioxide, a harmless gas, for easier viewing and to provide
room for the surgery to be performed. Next, two needles-like instruments are inserted
at a different place. These instruments serve as tiny hands within the abdomen.
They can pick up the gallbladder, move intestines around, and generally assist the
surgeon. Finally, several different instruments are inserted to clip the gallbladder
artery and bile duct, and to safely dissect and remove the gallbladder and stones.
When the gallbladder is freed, it is then eased out of the tiny navel incision.
The entire procedure normally takes 60 minutes. The three puncture wounds require
no stitches and may leave very slight blemishes. The navel incision is barely visible.
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After the Procedure
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After the procedure, the patient is taken to the recovery room for observation.
The recovery process will vary depending upon the type of procedure performed and
the type of anesthesia that is given. Once the blood pressure, pulse, and breathing
are stable and the patient is alert, they are shifted to the hospital room. It is
common to feel groggy and nauseated soon after surgery and medication is available
to help with these discomforts.
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Benefits and drawbacks
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Using advanced laparoscopic technology, it is now possible to remove the gallbladder
through a tiny incision at the navel! With new video technology, the laparoscope
has become a miniature television camera. Powerful magnification is now possible,
showing the intestinal organs in great detail. It is an exciting development because
it offers so much to the patient like :
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- Less postoperative pain because it does not require the abdominal muscles to be
cut
- Shortens hospital stay
- May result in a quicker return to bowel function
- Quicker return to normal activity
- Better cosmetic results
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But while the procedure seems very easy for the patient, it is still an abdominal
surgery. In many instances, the surgeon may not recommend this procedure. To decide
upon the technique, the surgeon has to carefully evaluate each case and weigh the
benefit for the patient against the risks. However, in the presence of infection,
adhesions, or variations in anatomy, this method becomes dangerous and your surgeon
may need to make the prudent decision to continue by making the traditional incision
to safely complete the operation. This should not be seen as a failure, but as a
wise decision by your surgeon to prevent dangerous complications. In about 5 to
10% of cases, the gallbladder cannot be safely removed by laparoscopy. In these
cases, standard open abdominal surgery has to be the mode of treatment. The table
given below compares the laparoscopic and open surgery.
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LAPAROSCOPIC
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OPEN
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 Small Incisions (less than
½ an inch)
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 Large Incision
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 Hospital stay is 1 to 3 days
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 Hospital stay of about 5 days
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 Patients usually return to
work in 5 to 10 days
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 Return to work in about 4 weeks
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 Lesser risk of Infection
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 Greater risk of infection
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 Less pain
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 More painful
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 Less chance of hernias
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 More chance of hernias
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Complications
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An uncommon but potentially serious complication with the new procedure is injury
to the common bile duct, which connects the gallbladder and liver. An injured bile
duct can leak bile and cause a painful and potentially dangerous infection. Many
cases of minor injury to the common bile duct can be managed non-surgically. Major
injury to the bile duct, however, is a very serious problem and may require corrective
surgery. At this time it is unclear whether these complications are more common
following laparoscopic cholecystectomy than following standard cholecystectomy.
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Care at home
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Once the patient is back at home, it is important to keep the incision clean and
dry. The physician will give specific bathing instructions. If stitches or surgical
staples are used, they will be removed during a follow-up office visit. If adhesive
strips are used, they should be kept dry and generally will fall off within a few
days.
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The incision and the abdominal muscles may ache, especially after long periods of
standing. Pain relievers for soreness can be taken as recommended by the physician.
Aspirin or certain other pain medications may increase the chance of bleeding. Patients
must ensure that they take only recommended medications. Walking and limited movement
are generally encouraged, but strenuous activity should be avoided. The physician
will give proper instructions about when the patient can return to work and resume
normal activities.
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