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Besides ART, there are also other procedures which
are carried out depending upon the age of the couple
and the problem. In this day and age more and more career
oriented women are getting married late in life. By
the time they start planning to have children; they
are nearing the fourth decade of their life (40 years).
Women after the age of 40 tend to have fewer eggs in
their ovaries or the quality of the eggs they produce
may be poor. Thus, even new technologies like IVF and
ICSI may not ensure a successful pregnancy. Furthermore,
after the age of 40 to 42, many women stop producing
eggs as they enter the stage of Perimenopause (decreased
periods) or menopause (stoppage of periods). So this
new technique of Egg Donation has come as a blessing
to many such women. Besides this, medical science has
also grown to the extent that it can now bring joy of
hope to couples who are carriers of any genetic disorder.
Aastha offers the following new technologies (egg donation,
PGD, cryopreservation):
Egg Donation
In
egg donation, eggs are borrowed from a young woman (less
than 33 yrs of age) called the donor, with her consent.
These eggs are then fertilized with the sperms of the
husband of the recipient woman and the resultant embryo
(the earliest form of the baby), is inserted into the
womb of the recipient. The success rate of this procedure
is in the region of 30 to 40%. Besides elderly or menopausal
women, egg donation can be done in younger women whose
ovaries have prematurely failed or in young women who
have undergone radiation or chemotherapy for cancer.
Radiation or chemotherapy destroys the eggs and hence
these women have a failure of their ovaries. Egg donation
is also used in patients who are carrying major chromosomal
defects so that they do not pass the genetic defect
to their children.
Our proficient staff will coordinate the cycles of
the donor and recipient to accomplish a fresh embryo
transfer whenever possible.
Pre-Implantation
Genetic Diagnosis (PGD)
Pre-Implantation Genetic Diagnosis (PGD) is the newest
procedure for detecting abnormalities in early-fertilized
egg and embryos. PGD is the testing of embryos for genetic
abnormalities before transferring to the uterus. PGD
is typically used if there is a family history of a
particular genetic disorder. We offer PGD to couples
who have or are carriers of specific genetic disorders.
PGD testing can help ensure that healthy embryos are
selected for transfer to the uterus.
Abnormal or "unbalanced" chromosomes may
result in an embryo not implanting, increased rate of
pregnancy loss or result in a child afflicted with severe
physical and/or mental problem. For couples who wish
to use the services of PDG, we will coordinate your
infertility treatment with a cooperating PGD Centre
so that your ease of care can be maintained.
Surgical
and Non Surgical Sperm Aspiration techniques
When the Semen Analysis shows very poor results many
techniques such are used to retrieve sperm for the IVF
or ICSI program. The Various techniques are: Vasectomy
Reversal, Microscopic Vasovasostomy, Microscopic Epididymal
Sperm Aspiration (MESA), Testicular Sperm Retrieval
from Biopsy (TESA) and many more.
Sperm retrieval from Testicular Biopsy (TESA) is the
most commonly practised procedure. Multiple biopsies
have successfully retrieved mature sperm from over 60%
of male patients diagnosed as Sertoli cell only syndrome
(SCOS) cases.
Cryopreservation
Cryopreservation or freezing allows preservation of
sperms in future spontaneous ovulation cycles and embryos
in future frozen cycles of IVF. This is an advantage
if many eggs are retrieved and fertilized.
Embryo freezing
Saving
eggs for future use by fertilizing them with sperm and
then freezing them as pre-embryos can be helpful. Frozen
pre-embryos can be transferred during subsequent spontaneous
(natural) ovulation cycles without subjecting the woman
to any additional medications and egg retrieval. At
the right time during succeeding treatment cycles, the
frozen pre embryos are thawed & transferred into
the uterus.
Sperm Banking
Cryopreservation of sperms also is particularly useful
when the husband is not living with the wife. This allows
the wife to go ahead with the IVF program while the
husband is away. Sperm freezing is also relevant for
patients undergoing surgery or radiation or chemotherapy
that can affect their fertility. Sperm can be frozen
before the therapy and maybe later used for an IVF or
ICSI program if desired.
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